Atomistry » Caesium » PDB 6dzo-7jmq » 6vfd
Atomistry »
  Caesium »
    PDB 6dzo-7jmq »
      6vfd »

Caesium in PDB 6vfd: Tryptophan Synthase Mutant Q114A in Complex with Cesium Ion at the Metal Coordination Site and 2-Aminophenol Quinonoid at the Enzyme Beta Site

Enzymatic activity of Tryptophan Synthase Mutant Q114A in Complex with Cesium Ion at the Metal Coordination Site and 2-Aminophenol Quinonoid at the Enzyme Beta Site

All present enzymatic activity of Tryptophan Synthase Mutant Q114A in Complex with Cesium Ion at the Metal Coordination Site and 2-Aminophenol Quinonoid at the Enzyme Beta Site:
4.2.1.20;

Protein crystallography data

The structure of Tryptophan Synthase Mutant Q114A in Complex with Cesium Ion at the Metal Coordination Site and 2-Aminophenol Quinonoid at the Enzyme Beta Site, PDB code: 6vfd was solved by E.Hilario, L.Fan, M.F.Dunn, L.J.Mueller, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 29.69 / 1.70
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 183.079, 59.340, 67.440, 90.00, 94.85, 90.00
R / Rfree (%) 19.5 / 22.4

Other elements in 6vfd:

The structure of Tryptophan Synthase Mutant Q114A in Complex with Cesium Ion at the Metal Coordination Site and 2-Aminophenol Quinonoid at the Enzyme Beta Site also contains other interesting chemical elements:

Chlorine (Cl) 16 atoms

Caesium Binding Sites:

The binding sites of Caesium atom in the Tryptophan Synthase Mutant Q114A in Complex with Cesium Ion at the Metal Coordination Site and 2-Aminophenol Quinonoid at the Enzyme Beta Site (pdb code 6vfd). This binding sites where shown within 5.0 Angstroms radius around Caesium atom.
In total 4 binding sites of Caesium where determined in the Tryptophan Synthase Mutant Q114A in Complex with Cesium Ion at the Metal Coordination Site and 2-Aminophenol Quinonoid at the Enzyme Beta Site, PDB code: 6vfd:
Jump to Caesium binding site number: 1; 2; 3; 4;

Caesium binding site 1 out of 4 in 6vfd

Go back to Caesium Binding Sites List in 6vfd
Caesium binding site 1 out of 4 in the Tryptophan Synthase Mutant Q114A in Complex with Cesium Ion at the Metal Coordination Site and 2-Aminophenol Quinonoid at the Enzyme Beta Site


Mono view


Stereo pair view

A full contact list of Caesium with other atoms in the Cs binding site number 1 of Tryptophan Synthase Mutant Q114A in Complex with Cesium Ion at the Metal Coordination Site and 2-Aminophenol Quinonoid at the Enzyme Beta Site within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cs414

b:23.7
occ:0.78
 O B:THR71 3.0 18.7 1.0
O B:THR69 3.1 27.4 1.0
O B:THR66 3.2 25.1 1.0
O B:HOH596 3.2 33.5 1.0
OG1 B:THR66 3.4 22.3 1.0
O B:HOH850 3.4 40.0 1.0
O B:HOH853 3.7 35.1 1.0
O B:HOH947 3.8 51.7 1.0
O B:HOH804 3.8 49.0 1.0
C B:THR66 3.9 24.8 1.0
CB B:THR66 3.9 22.1 1.0
C B:THR69 4.1 26.3 1.0
C B:THR71 4.1 17.7 1.0
OG1 B:THR69 4.3 22.6 1.0
N B:THR71 4.5 18.2 1.0
O B:HOH760 4.5 48.9 1.0
CA B:THR66 4.6 23.2 1.0
N B:ALA67 4.6 25.2 1.0
N B:THR69 4.6 27.4 1.0
O B:HOH576 4.7 16.6 1.0
CA B:ALA67 4.7 27.3 1.0
CA B:ARG70 4.9 25.9 1.0
CA B:THR69 4.9 26.6 1.0
N B:ARG70 4.9 25.8 1.0
C B:ARG70 4.9 23.5 1.0
N B:THR72 4.9 17.8 1.0
N B:GLY68 4.9 29.6 1.0
CA B:THR71 4.9 17.5 1.0

Caesium binding site 2 out of 4 in 6vfd

Go back to Caesium Binding Sites List in 6vfd
Caesium binding site 2 out of 4 in the Tryptophan Synthase Mutant Q114A in Complex with Cesium Ion at the Metal Coordination Site and 2-Aminophenol Quinonoid at the Enzyme Beta Site


Mono view


Stereo pair view

A full contact list of Caesium with other atoms in the Cs binding site number 2 of Tryptophan Synthase Mutant Q114A in Complex with Cesium Ion at the Metal Coordination Site and 2-Aminophenol Quinonoid at the Enzyme Beta Site within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cs415

b:21.0
occ:0.85
 CS B:CS415 0.0 21.0 0.8
CS B:CS415 2.5 22.8 0.1
O B:GLY232 2.9 19.6 1.0
O B:PHE306 2.9 19.9 1.0
O B:GLY268 3.0 16.0 1.0
O B:LEU304 3.3 15.5 1.0
O B:SER308 3.5 15.9 1.0
O B:VAL231 3.6 17.6 1.0
C B:GLY232 3.8 18.4 1.0
C B:PHE306 4.0 20.8 1.0
C B:GLY268 4.0 14.8 1.0
CA B:GLY232 4.0 17.9 1.0
CD B:PRO270 4.2 14.7 1.0
CD B:PRO257 4.2 13.4 1.0
N B:PHE306 4.3 20.3 1.0
CB B:PHE306 4.3 20.8 1.0
C B:LEU304 4.4 16.6 1.0
C B:VAL231 4.4 16.6 1.0
CG B:PRO257 4.4 13.6 1.0
CA B:PHE306 4.5 21.0 1.0
CA B:GLY268 4.5 14.9 1.0
CG B:PRO270 4.6 15.0 1.0
N B:GLY232 4.7 16.8 1.0
C B:SER308 4.7 16.2 1.0
OE2 B:GLU256 4.9 17.9 1.0
N B:SER308 5.0 18.3 1.0
CD2 B:PHE306 5.0 21.2 1.0

Caesium binding site 3 out of 4 in 6vfd

Go back to Caesium Binding Sites List in 6vfd
Caesium binding site 3 out of 4 in the Tryptophan Synthase Mutant Q114A in Complex with Cesium Ion at the Metal Coordination Site and 2-Aminophenol Quinonoid at the Enzyme Beta Site


Mono view


Stereo pair view

A full contact list of Caesium with other atoms in the Cs binding site number 3 of Tryptophan Synthase Mutant Q114A in Complex with Cesium Ion at the Metal Coordination Site and 2-Aminophenol Quinonoid at the Enzyme Beta Site within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cs415

b:22.8
occ:0.15
 CS B:CS415 0.0 22.8 0.1
CS B:CS415 2.5 21.0 0.8
OE2 B:GLU256 2.9 17.9 1.0
O B:VAL231 3.4 17.6 1.0
O B:SER308 3.5 15.9 1.0
O B:GLY268 3.6 16.0 1.0
CG1 B:VAL231 3.7 15.7 1.0
CD B:PRO270 3.7 14.7 1.0
O B:GLY232 3.8 19.6 1.0
CD B:GLU256 3.8 16.4 1.0
CG B:GLU256 3.8 15.7 1.0
CB B:VAL309 3.9 15.6 1.0
CG2 B:VAL309 4.0 15.0 1.0
CG B:PRO270 4.0 15.0 1.0
C B:VAL231 4.1 16.6 1.0
CB B:VAL231 4.3 15.6 1.0
CB B:GLU256 4.4 14.2 1.0
C B:GLY232 4.5 18.4 1.0
C B:SER308 4.5 16.2 1.0
CA B:VAL309 4.6 15.4 1.0
C B:GLY268 4.7 14.8 1.0
CD B:PRO257 4.8 13.4 1.0
N B:PRO270 4.8 15.3 1.0
N B:GLY232 4.8 16.8 1.0
CA B:GLY232 4.8 17.9 1.0
O B:PHE306 4.9 19.9 1.0
CA B:VAL231 4.9 15.4 1.0
CA B:GLU256 4.9 13.2 1.0
CA B:ALA269 4.9 14.9 1.0
CG1 B:VAL309 5.0 16.7 1.0
OE1 B:GLU256 5.0 17.7 1.0
N B:VAL309 5.0 15.9 1.0

Caesium binding site 4 out of 4 in 6vfd

Go back to Caesium Binding Sites List in 6vfd
Caesium binding site 4 out of 4 in the Tryptophan Synthase Mutant Q114A in Complex with Cesium Ion at the Metal Coordination Site and 2-Aminophenol Quinonoid at the Enzyme Beta Site


Mono view


Stereo pair view

A full contact list of Caesium with other atoms in the Cs binding site number 4 of Tryptophan Synthase Mutant Q114A in Complex with Cesium Ion at the Metal Coordination Site and 2-Aminophenol Quinonoid at the Enzyme Beta Site within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cs416

b:18.4
occ:0.40
 O B:PRO56 3.1 17.4 1.0
O B:GLY54 3.2 20.0 1.0
O B:DMS409 3.2 21.9 0.9
O B:HOH719 3.8 26.7 1.0
O B:HOH772 4.0 22.8 1.0
C1 B:DMS409 4.1 19.9 0.9
C B:PRO56 4.3 16.7 1.0
S B:DMS409 4.3 23.5 0.9
C B:GLY54 4.3 18.2 1.0
N B:PRO56 4.5 17.7 1.0
C B:ARG55 4.6 17.8 1.0
CD B:PRO56 4.7 19.9 1.0
O B:ARG55 4.8 18.1 1.0
C2 B:DMS409 4.9 20.3 0.9
CG B:PRO56 5.0 19.6 1.0

Reference:

E.Hilario, L.Fan, M.F.Dunn, L.J.Mueller. Tryptophan Synthase Mutant Q114A in Complex with Cesium Ion at the Metal Coordination Site and 2-Aminophenol Quinonoid at the Enzyme Beta Site. To Be Published.
Page generated: Tue Jul 30 20:58:26 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy