Atomistry » Caesium » PDB 6dzo-7kjb » 6fvr
Atomistry »
  Caesium »
    PDB 6dzo-7kjb »
      6fvr »

Caesium in PDB 6fvr: The Active Form of A Pentameric Ion Channel (Stelic) Gated By Alkaline pH - Stelic in Complex with Cesium Ions (Cs+)

Protein crystallography data

The structure of The Active Form of A Pentameric Ion Channel (Stelic) Gated By Alkaline pH - Stelic in Complex with Cesium Ions (Cs+), PDB code: 6fvr was solved by H.Hu, M.Delarue, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 20.00 / 4.20
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 221.169, 114.107, 144.274, 90.00, 111.75, 90.00
R / Rfree (%) 22.5 / 23.4

Caesium Binding Sites:

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 11;

Binding sites:

The binding sites of Caesium atom in the The Active Form of A Pentameric Ion Channel (Stelic) Gated By Alkaline pH - Stelic in Complex with Cesium Ions (Cs+) (pdb code 6fvr). This binding sites where shown within 5.0 Angstroms radius around Caesium atom.
In total 11 binding sites of Caesium where determined in the The Active Form of A Pentameric Ion Channel (Stelic) Gated By Alkaline pH - Stelic in Complex with Cesium Ions (Cs+), PDB code: 6fvr:
Jump to Caesium binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Caesium binding site 1 out of 11 in 6fvr

Go back to Caesium Binding Sites List in 6fvr
Caesium binding site 1 out of 11 in the The Active Form of A Pentameric Ion Channel (Stelic) Gated By Alkaline pH - Stelic in Complex with Cesium Ions (Cs+)


Mono view


Stereo pair view

A full contact list of Caesium with other atoms in the Cs binding site number 1 of The Active Form of A Pentameric Ion Channel (Stelic) Gated By Alkaline pH - Stelic in Complex with Cesium Ions (Cs+) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cs402

b:30.0
occ:0.50
O A:PHE78 3.0 27.4 1.0
CE1 A:PHE78 3.7 26.3 1.0
ND2 E:ASN91 3.8 42.9 1.0
CD1 A:PHE78 4.0 27.2 1.0
C A:PHE78 4.1 28.7 1.0
CZ A:PHE78 4.2 26.9 1.0
O E:GLN90 4.2 40.5 1.0
CG E:ASN91 4.6 66.4 1.0
CG A:PHE78 4.6 28.9 1.0
OD1 E:ASN91 4.7 66.7 1.0
CE2 A:PHE78 4.7 28.5 1.0
CA A:THR79 4.7 26.1 1.0
CE2 A:TYR80 4.8 23.4 1.0
NH2 A:ARG92 4.8 31.3 1.0
N A:THR79 4.8 27.9 1.0
CD2 A:TYR80 4.9 23.1 1.0
CD2 A:PHE78 4.9 29.6 1.0

Caesium binding site 2 out of 11 in 6fvr

Go back to Caesium Binding Sites List in 6fvr
Caesium binding site 2 out of 11 in the The Active Form of A Pentameric Ion Channel (Stelic) Gated By Alkaline pH - Stelic in Complex with Cesium Ions (Cs+)


Mono view


Stereo pair view

A full contact list of Caesium with other atoms in the Cs binding site number 2 of The Active Form of A Pentameric Ion Channel (Stelic) Gated By Alkaline pH - Stelic in Complex with Cesium Ions (Cs+) within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cs402

b:30.0
occ:0.50
O B:GLU27 3.3 8.7 1.0
O A:GLY158 3.6 17.6 1.0
O A:THR21 3.8 22.2 1.0
C B:GLU27 3.8 8.8 1.0
OE1 A:GLU159 3.9 73.2 1.0
CA B:GLU27 4.0 10.4 1.0
C A:THR21 4.2 20.0 1.0
O A:ILE20 4.3 17.0 1.0
OE1 B:GLU28 4.6 9.5 1.0
O B:LYS26 4.6 9.4 1.0
C A:GLY158 4.6 16.4 1.0
N A:GLY22 4.6 17.9 1.0
CA A:GLY22 4.7 17.5 1.0
CA A:GLU159 4.7 14.8 1.0
CD A:GLU159 4.8 54.6 1.0
CB B:GLU27 4.8 12.7 1.0
N B:GLU28 4.8 8.1 1.0
CA A:THR21 5.0 20.2 1.0
CB B:GLU28 5.0 8.0 1.0

Caesium binding site 3 out of 11 in 6fvr

Go back to Caesium Binding Sites List in 6fvr
Caesium binding site 3 out of 11 in the The Active Form of A Pentameric Ion Channel (Stelic) Gated By Alkaline pH - Stelic in Complex with Cesium Ions (Cs+)


Mono view


Stereo pair view

A full contact list of Caesium with other atoms in the Cs binding site number 3 of The Active Form of A Pentameric Ion Channel (Stelic) Gated By Alkaline pH - Stelic in Complex with Cesium Ions (Cs+) within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cs403

b:30.0
occ:0.50
OE1 B:GLU159 3.1 16.1 1.0
O B:GLY158 3.4 30.2 1.0
O B:THR21 3.9 27.0 1.0
CD B:GLU159 4.0 15.1 1.0
O B:ILE20 4.1 21.8 1.0
O C:GLU27 4.1 15.2 1.0
CA B:GLU159 4.1 19.9 1.0
C B:THR21 4.2 23.8 1.0
CA B:GLY22 4.4 18.3 1.0
C B:GLY158 4.4 28.1 1.0
N B:GLY22 4.4 19.7 1.0
OE2 B:GLU159 4.5 13.9 1.0
N B:GLU160 4.6 21.2 1.0
C C:GLU27 4.6 13.9 1.0
OE1 C:GLU28 4.7 23.9 1.0
N B:GLU159 4.7 23.1 1.0
CA C:GLU27 4.8 15.6 1.0
CB B:GLU159 4.8 15.6 1.0
C B:GLU159 4.9 20.5 1.0
CG B:GLU159 5.0 13.5 1.0

Caesium binding site 4 out of 11 in 6fvr

Go back to Caesium Binding Sites List in 6fvr
Caesium binding site 4 out of 11 in the The Active Form of A Pentameric Ion Channel (Stelic) Gated By Alkaline pH - Stelic in Complex with Cesium Ions (Cs+)


Mono view


Stereo pair view

A full contact list of Caesium with other atoms in the Cs binding site number 4 of The Active Form of A Pentameric Ion Channel (Stelic) Gated By Alkaline pH - Stelic in Complex with Cesium Ions (Cs+) within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cs404

b:30.0
occ:0.50
O B:PHE78 2.9 16.4 1.0
CE1 B:PHE78 3.0 15.6 1.0
CD1 B:PHE78 3.3 16.1 1.0
CZ B:PHE78 3.4 16.1 1.0
C B:PHE78 3.9 17.6 1.0
CG B:PHE78 3.9 17.3 1.0
CE2 B:PHE78 4.0 16.8 1.0
ND2 A:ASN91 4.1 34.2 1.0
CD2 B:PHE78 4.2 17.5 1.0
CE2 B:TYR80 4.6 14.1 1.0
N B:THR79 4.7 17.8 1.0
CA B:PHE78 4.7 19.4 1.0
CA B:THR79 4.7 16.3 1.0
N B:PHE78 4.7 19.4 1.0
OE2 B:GLU106 4.7 19.0 1.0
CD2 B:TYR80 4.8 13.5 1.0
OE1 B:GLU106 4.9 17.5 1.0
CB B:PHE78 4.9 19.1 1.0
O A:GLN90 4.9 39.4 1.0
NH2 B:ARG92 5.0 21.5 1.0
CG A:ASN91 5.0 32.1 1.0

Caesium binding site 5 out of 11 in 6fvr

Go back to Caesium Binding Sites List in 6fvr
Caesium binding site 5 out of 11 in the The Active Form of A Pentameric Ion Channel (Stelic) Gated By Alkaline pH - Stelic in Complex with Cesium Ions (Cs+)


Mono view


Stereo pair view

A full contact list of Caesium with other atoms in the Cs binding site number 5 of The Active Form of A Pentameric Ion Channel (Stelic) Gated By Alkaline pH - Stelic in Complex with Cesium Ions (Cs+) within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cs402

b:30.0
occ:0.50
O C:PHE78 3.0 30.0 1.0
ND2 B:ASN91 3.6 49.9 1.0
CE1 C:PHE78 3.9 25.1 1.0
O B:GLN90 4.0 49.6 1.0
C C:PHE78 4.1 29.4 1.0
CD1 C:PHE78 4.1 26.0 1.0
CZ C:PHE78 4.3 25.9 1.0
CG B:ASN91 4.3 48.8 1.0
OD1 B:ASN91 4.4 46.0 1.0
CA C:THR79 4.6 27.6 1.0
CG C:PHE78 4.7 27.7 1.0
N C:THR79 4.7 28.4 1.0
CD2 C:TYR80 4.8 21.6 1.0
CE2 C:TYR80 4.8 21.3 1.0
C B:GLN90 4.9 45.6 1.0
CE2 C:PHE78 4.9 27.5 1.0
NH2 C:ARG92 5.0 30.5 1.0

Caesium binding site 6 out of 11 in 6fvr

Go back to Caesium Binding Sites List in 6fvr
Caesium binding site 6 out of 11 in the The Active Form of A Pentameric Ion Channel (Stelic) Gated By Alkaline pH - Stelic in Complex with Cesium Ions (Cs+)


Mono view


Stereo pair view

A full contact list of Caesium with other atoms in the Cs binding site number 6 of The Active Form of A Pentameric Ion Channel (Stelic) Gated By Alkaline pH - Stelic in Complex with Cesium Ions (Cs+) within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cs403

b:30.0
occ:0.50
O C:GLY158 3.2 6.7 1.0
O D:GLU27 3.5 18.8 1.0
O C:THR21 3.8 11.5 1.0
OE1 C:GLU159 3.8 7.1 1.0
O C:ILE20 3.9 7.3 1.0
C C:THR21 4.1 9.7 1.0
C D:GLU27 4.1 18.2 1.0
C C:GLY158 4.2 6.7 1.0
CA C:GLU159 4.4 6.7 1.0
OE1 D:GLU28 4.4 36.5 1.0
CA D:GLU27 4.5 19.1 1.0
N C:GLY22 4.5 8.5 1.0
CD C:GLU159 4.7 6.8 1.0
CA C:GLY22 4.7 8.4 1.0
N C:GLU159 4.7 7.0 1.0
CA C:THR21 4.8 9.6 1.0
C C:ILE20 5.0 7.7 1.0
N C:GLU160 5.0 6.2 1.0
CB D:GLU28 5.0 16.8 1.0

Caesium binding site 7 out of 11 in 6fvr

Go back to Caesium Binding Sites List in 6fvr
Caesium binding site 7 out of 11 in the The Active Form of A Pentameric Ion Channel (Stelic) Gated By Alkaline pH - Stelic in Complex with Cesium Ions (Cs+)


Mono view


Stereo pair view

A full contact list of Caesium with other atoms in the Cs binding site number 7 of The Active Form of A Pentameric Ion Channel (Stelic) Gated By Alkaline pH - Stelic in Complex with Cesium Ions (Cs+) within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cs402

b:30.0
occ:0.50
O D:PHE78 3.7 32.7 1.0
CE1 D:PHE78 3.8 32.5 1.0
CZ D:PHE78 4.1 33.8 1.0
NH2 D:ARG92 4.2 35.5 1.0
O C:GLN90 4.2 24.4 1.0
CD1 D:PHE78 4.3 32.5 1.0
ND2 C:ASN91 4.4 24.9 1.0
OE2 D:GLU106 4.4 36.9 1.0
CE2 D:TYR80 4.5 28.6 1.0
CD2 D:TYR80 4.7 28.0 1.0
OE1 D:GLU106 4.7 31.6 1.0
C D:PHE78 4.8 32.6 1.0
CE2 D:PHE78 4.8 36.2 1.0
CG D:PHE78 5.0 33.8 1.0

Caesium binding site 8 out of 11 in 6fvr

Go back to Caesium Binding Sites List in 6fvr
Caesium binding site 8 out of 11 in the The Active Form of A Pentameric Ion Channel (Stelic) Gated By Alkaline pH - Stelic in Complex with Cesium Ions (Cs+)


Mono view


Stereo pair view

A full contact list of Caesium with other atoms in the Cs binding site number 8 of The Active Form of A Pentameric Ion Channel (Stelic) Gated By Alkaline pH - Stelic in Complex with Cesium Ions (Cs+) within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cs403

b:30.0
occ:0.50
O D:GLY158 3.3 16.7 1.0
OE1 D:GLU159 3.4 76.6 1.0
O D:THR21 3.8 21.1 1.0
O E:GLU27 3.9 27.9 1.0
O D:ILE20 3.9 19.3 1.0
C D:THR21 4.1 20.2 1.0
CA D:GLU159 4.2 18.6 1.0
CD D:GLU159 4.2 78.4 1.0
C D:GLY158 4.3 17.6 1.0
N D:GLY22 4.4 19.0 1.0
CA D:GLY22 4.4 18.4 1.0
C E:GLU27 4.5 26.7 1.0
OE1 E:GLU28 4.6 94.5 1.0
N D:GLU159 4.7 18.3 1.0
CA E:GLU27 4.7 26.5 1.0
N D:GLU160 4.8 16.8 1.0
OE2 D:GLU159 4.8 78.9 1.0
CA D:THR21 4.8 20.7 1.0
CB D:GLU159 4.9 19.3 1.0
C D:ILE20 5.0 19.6 1.0

Caesium binding site 9 out of 11 in 6fvr

Go back to Caesium Binding Sites List in 6fvr
Caesium binding site 9 out of 11 in the The Active Form of A Pentameric Ion Channel (Stelic) Gated By Alkaline pH - Stelic in Complex with Cesium Ions (Cs+)


Mono view


Stereo pair view

A full contact list of Caesium with other atoms in the Cs binding site number 9 of The Active Form of A Pentameric Ion Channel (Stelic) Gated By Alkaline pH - Stelic in Complex with Cesium Ions (Cs+) within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Cs402

b:30.0
occ:0.50
OE1 E:GLU159 3.4 25.3 1.0
O E:GLY158 3.6 30.1 1.0
O E:THR21 3.8 24.8 1.0
O A:GLU27 3.8 16.6 1.0
C E:THR21 4.2 24.3 1.0
O E:ILE20 4.3 22.7 1.0
CD E:GLU159 4.3 53.5 1.0
C A:GLU27 4.3 15.9 1.0
CA E:GLY22 4.4 22.8 1.0
CA A:GLU27 4.4 18.0 1.0
CA E:GLU159 4.4 26.9 1.0
N E:GLY22 4.5 23.4 1.0
C E:GLY158 4.6 30.1 1.0
O A:LYS26 4.7 16.5 1.0
OE1 A:GLU28 4.7 69.5 1.0
OE2 E:GLU159 4.8 30.8 1.0
N E:GLU160 4.9 29.7 1.0
N E:GLU159 5.0 28.2 1.0

Caesium binding site 10 out of 11 in 6fvr

Go back to Caesium Binding Sites List in 6fvr
Caesium binding site 10 out of 11 in the The Active Form of A Pentameric Ion Channel (Stelic) Gated By Alkaline pH - Stelic in Complex with Cesium Ions (Cs+)


Mono view


Stereo pair view

A full contact list of Caesium with other atoms in the Cs binding site number 10 of The Active Form of A Pentameric Ion Channel (Stelic) Gated By Alkaline pH - Stelic in Complex with Cesium Ions (Cs+) within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Cs403

b:30.0
occ:0.50
O E:PHE78 3.4 66.2 1.0
CE1 E:PHE78 3.5 66.6 1.0
CZ E:PHE78 3.8 65.2 1.0
CD1 E:PHE78 3.9 67.6 1.0
ND2 D:ASN91 4.3 36.1 1.0
C E:PHE78 4.4 67.3 1.0
NH2 E:ARG92 4.4 30.6 1.0
CE2 E:PHE78 4.5 68.8 1.0
OE2 E:GLU106 4.5 77.9 1.0
O D:GLN90 4.5 38.8 1.0
CG E:PHE78 4.6 66.1 1.0
CE2 E:TYR80 4.6 52.1 1.0
CD2 E:PHE78 4.8 67.8 1.0
CD2 E:TYR80 4.8 51.7 1.0
OE1 E:GLU106 4.8 55.9 1.0

Reference:

H.Hu, A.Nemecz, C.Van Renterghem, Z.Fourati, L.Sauguet, P.J.Corringer, M.Delarue. Crystal Structures of A Pentameric Ion Channel Gated By Alkaline pH Show A Widely Open Pore and Identify A Cavity For Modulation. Proc. Natl. Acad. Sci. V. 115 E3959 2018U.S.A..
ISSN: ESSN 1091-6490
PubMed: 29632192
DOI: 10.1073/PNAS.1717700115
Page generated: Sun Dec 13 10:57:09 2020

Last articles

Zn in 7M6U
Zn in 7NNG
Zn in 7NEE
Zn in 7NEU
Zn in 7M3K
Zn in 7KWD
Zn in 7KYH
Zn in 7KNG
Zn in 7KY2
Zn in 7KYF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy