Caesium in PDB 3ij4: Cesium Sites in the Crystal Structure of A Functional Acid Sensing Ion Channel in the Desensitized State

The structure of Cesium Sites in the Crystal Structure of A Functional Acid Sensing Ion Channel in the Desensitized State, PDB code: 3ij4 was solved by E.B.Gonzales, E.Gouaux, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	27.47 / 3.00
Space group	H 3
Cell size a, b, c (Å), α, β, γ (°)	131.787, 131.787, 119.107, 90.00, 90.00, 120.00
R / Rfree (%)	22.3 / 27.2

The structure of Cesium Sites in the Crystal Structure of A Functional Acid Sensing Ion Channel in the Desensitized State also contains other interesting chemical elements:

Chlorine

(Cl)

1 atom

The binding sites of Caesium atom in the Cesium Sites in the Crystal Structure of A Functional Acid Sensing Ion Channel in the Desensitized State (pdb code 3ij4). This binding sites where shown within 5.0 Angstroms radius around Caesium atom.
In total 4 binding sites of Caesium where determined in the Cesium Sites in the Crystal Structure of A Functional Acid Sensing Ion Channel in the Desensitized State, PDB code: 3ij4:
Jump to Caesium binding site number: 1; 2; 3; 4;

Caesium binding site 1 out of 4 in the Cesium Sites in the Crystal Structure of A Functional Acid Sensing Ion Channel in the Desensitized State


Mono view


Stereo pair view

A full contact list of Caesium with other atoms in the Cs binding site number 1 of Cesium Sites in the Crystal Structure of A Functional Acid Sensing Ion Channel in the Desensitized State within 5.0Å range: probe atom residue distance (Å) B Occ A:Cs467 b:30.0 occ:1.00 O A:THR240 2.8 36.7 1.0 O A:THR237 3.3 39.8 1.0 C A:THR240 4.0 36.6 1.0 CA A:ASP238 4.0 38.6 1.0 O A:ASP238 4.0 38.4 1.0 C A:ASP238 4.0 38.4 1.0 C A:THR237 4.3 39.7 1.0 O A:HOH480 4.5 48.3 1.0 N A:ASP238 4.6 39.1 1.0 CA A:SER241 4.6 35.6 1.0 O A:HOH471 4.7 30.7 1.0 N A:GLU239 4.7 38.0 1.0 N A:THR240 4.7 37.1 1.0 O A:HOH472 4.7 30.9 1.0 N A:SER241 4.7 36.2 1.0 CB A:SER241 4.9 35.9 1.0 CA A:THR240 5.0 36.9 1.0

Caesium binding site 2 out of 4 in the Cesium Sites in the Crystal Structure of A Functional Acid Sensing Ion Channel in the Desensitized State


Mono view


Stereo pair view

A full contact list of Caesium with other atoms in the Cs binding site number 2 of Cesium Sites in the Crystal Structure of A Functional Acid Sensing Ion Channel in the Desensitized State within 5.0Å range: probe atom residue distance (Å) B Occ A:Cs468 b:30.0 occ:1.00 O A:GLU299 2.2 66.7 1.0 O A:TYR301 3.2 61.3 1.0 C A:GLU299 3.4 66.7 1.0 C A:TYR301 3.7 61.3 1.0 N A:GLU299 4.0 68.1 1.0 CA A:ASP302 4.0 59.6 1.0 OD2 A:ASP297 4.0 70.2 1.0 N A:ASP302 4.1 60.5 1.0 CA A:GLU299 4.1 67.4 1.0 O A:SER298 4.2 68.9 1.0 C A:SER298 4.2 68.9 1.0 N A:TYR301 4.2 62.9 1.0 CB A:ASP302 4.3 59.7 1.0 C A:PHE300 4.4 63.9 1.0 N A:PHE300 4.4 65.7 1.0 CA A:TYR301 4.5 61.9 1.0 CA A:PHE300 4.7 64.7 1.0 O A:PHE300 4.8 63.7 1.0 N A:SER298 4.8 69.9 1.0

Caesium binding site 3 out of 4 in the Cesium Sites in the Crystal Structure of A Functional Acid Sensing Ion Channel in the Desensitized State


Mono view


Stereo pair view

A full contact list of Caesium with other atoms in the Cs binding site number 3 of Cesium Sites in the Crystal Structure of A Functional Acid Sensing Ion Channel in the Desensitized State within 5.0Å range: probe atom residue distance (Å) B Occ A:Cs469 b:30.0 occ:0.33 OD1 A:ASP433 2.7 76.7 1.0 CS A:CS470 3.4 30.0 0.3 CG A:ASP433 3.5 76.5 1.0 OD2 A:ASP433 3.5 76.4 1.0 O A:GLY429 4.7 69.4 1.0 CB A:ASP433 4.9 76.4 1.0 OH A:TYR425 5.0 61.5 1.0

Caesium binding site 4 out of 4 in the Cesium Sites in the Crystal Structure of A Functional Acid Sensing Ion Channel in the Desensitized State


Mono view


Stereo pair view

A full contact list of Caesium with other atoms in the Cs binding site number 4 of Cesium Sites in the Crystal Structure of A Functional Acid Sensing Ion Channel in the Desensitized State within 5.0Å range: probe atom residue distance (Å) B Occ A:Cs470 b:30.0 occ:0.33 OD1 A:ASP433 2.3 76.7 1.0 CG A:ASP433 3.0 76.5 1.0 O A:GLY432 3.0 75.2 1.0 CS A:CS469 3.4 30.0 0.3 OD2 A:ASP433 3.5 76.4 1.0 C A:GLY432 3.6 75.1 1.0 CA A:ASP433 3.7 76.4 1.0 N A:ASP433 3.9 75.7 1.0 CB A:ASP433 3.9 76.4 1.0 CA A:GLY432 4.7 74.5 1.0 O A:GLY429 4.8 69.4 1.0

E.B.Gonzales, T.Kawate, E.Gouaux. Pore Architecture and Ion Sites in Acid-Sensing Ion Channels and P2X Receptors. Nature V. 460 599 2009.
ISSN: ISSN 0028-0836
PubMed: 19641589
DOI: 10.1038/NATURE08218