Atomistry » Caesium » PDB 4hul-6dwe » 6c73
Atomistry »
  Caesium »
    PDB 4hul-6dwe »
      6c73 »

Caesium in PDB 6c73: Tryptophan Synthase Q114A Mutant (Internal Aldimine State) in Complex with N-(4'-Trifluoromethoxybenzenesulfonyl)-2-Amino-1-Ethylphosphate (F9F) with Cesium Ion Bound in the Metal Coordination Site

Enzymatic activity of Tryptophan Synthase Q114A Mutant (Internal Aldimine State) in Complex with N-(4'-Trifluoromethoxybenzenesulfonyl)-2-Amino-1-Ethylphosphate (F9F) with Cesium Ion Bound in the Metal Coordination Site

All present enzymatic activity of Tryptophan Synthase Q114A Mutant (Internal Aldimine State) in Complex with N-(4'-Trifluoromethoxybenzenesulfonyl)-2-Amino-1-Ethylphosphate (F9F) with Cesium Ion Bound in the Metal Coordination Site:
4.2.1.20;

Protein crystallography data

The structure of Tryptophan Synthase Q114A Mutant (Internal Aldimine State) in Complex with N-(4'-Trifluoromethoxybenzenesulfonyl)-2-Amino-1-Ethylphosphate (F9F) with Cesium Ion Bound in the Metal Coordination Site, PDB code: 6c73 was solved by E.Hilario, M.F.Dunn, L.J.Mueller, L.Fan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 19.82 / 1.65
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 181.609, 58.980, 67.150, 90.00, 94.40, 90.00
R / Rfree (%) 13.8 / 18.3

Other elements in 6c73:

The structure of Tryptophan Synthase Q114A Mutant (Internal Aldimine State) in Complex with N-(4'-Trifluoromethoxybenzenesulfonyl)-2-Amino-1-Ethylphosphate (F9F) with Cesium Ion Bound in the Metal Coordination Site also contains other interesting chemical elements:

Fluorine (F) 3 atoms
Chlorine (Cl) 1 atom

Caesium Binding Sites:

The binding sites of Caesium atom in the Tryptophan Synthase Q114A Mutant (Internal Aldimine State) in Complex with N-(4'-Trifluoromethoxybenzenesulfonyl)-2-Amino-1-Ethylphosphate (F9F) with Cesium Ion Bound in the Metal Coordination Site (pdb code 6c73). This binding sites where shown within 5.0 Angstroms radius around Caesium atom.
In total 5 binding sites of Caesium where determined in the Tryptophan Synthase Q114A Mutant (Internal Aldimine State) in Complex with N-(4'-Trifluoromethoxybenzenesulfonyl)-2-Amino-1-Ethylphosphate (F9F) with Cesium Ion Bound in the Metal Coordination Site, PDB code: 6c73:
Jump to Caesium binding site number: 1; 2; 3; 4; 5;

Caesium binding site 1 out of 5 in 6c73

Go back to Caesium Binding Sites List in 6c73
Caesium binding site 1 out of 5 in the Tryptophan Synthase Q114A Mutant (Internal Aldimine State) in Complex with N-(4'-Trifluoromethoxybenzenesulfonyl)-2-Amino-1-Ethylphosphate (F9F) with Cesium Ion Bound in the Metal Coordination Site


Mono view


Stereo pair view

A full contact list of Caesium with other atoms in the Cs binding site number 1 of Tryptophan Synthase Q114A Mutant (Internal Aldimine State) in Complex with N-(4'-Trifluoromethoxybenzenesulfonyl)-2-Amino-1-Ethylphosphate (F9F) with Cesium Ion Bound in the Metal Coordination Site within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cs313

b:40.6
occ:0.47
 O A:HOH671 3.0 42.5 1.0
O A:ALA167 3.1 19.6 1.0
O A:GLY170 3.2 19.7 1.0
O A:HIS204 3.6 18.7 1.0
O A:HOH492 3.7 27.9 1.0
N A:ALA206 4.1 16.0 1.0
NH2 A:ARG171 4.2 25.4 1.0
O A:HOH539 4.3 39.4 1.0
C A:GLY170 4.3 18.4 1.0
C A:ALA167 4.3 18.5 1.0
O A:SER168 4.3 21.4 0.8
CD A:ARG171 4.4 20.9 1.0
C A:ALA205 4.4 15.9 1.0
CA A:ALA205 4.5 15.1 1.0
O A:SER168 4.5 20.6 0.2
C A:HIS204 4.6 19.0 1.0
C A:SER168 4.8 20.1 0.8
CZ A:ARG171 4.8 25.7 1.0
C A:SER168 4.9 19.6 0.2
CA A:ALA206 4.9 14.3 1.0
NE A:ARG171 4.9 24.6 1.0
CB A:ALA206 5.0 15.4 1.0
CA A:ARG171 5.0 14.5 1.0

Caesium binding site 2 out of 5 in 6c73

Go back to Caesium Binding Sites List in 6c73
Caesium binding site 2 out of 5 in the Tryptophan Synthase Q114A Mutant (Internal Aldimine State) in Complex with N-(4'-Trifluoromethoxybenzenesulfonyl)-2-Amino-1-Ethylphosphate (F9F) with Cesium Ion Bound in the Metal Coordination Site


Mono view


Stereo pair view

A full contact list of Caesium with other atoms in the Cs binding site number 2 of Tryptophan Synthase Q114A Mutant (Internal Aldimine State) in Complex with N-(4'-Trifluoromethoxybenzenesulfonyl)-2-Amino-1-Ethylphosphate (F9F) with Cesium Ion Bound in the Metal Coordination Site within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cs417

b:24.6
occ:0.50
 CS B:CS417 0.0 24.6 0.5
CS B:CS417 1.9 18.5 0.4
O B:GLY268 3.0 10.6 1.0
O B:PHE306 3.1 21.3 1.0
O B:GLY232 3.1 20.7 1.0
O B:SER308 3.7 12.8 1.0
O B:LEU304 3.8 22.6 1.0
O B:VAL231 3.8 10.2 1.0
OG B:SER297 3.9 26.4 1.0
C B:GLY232 3.9 13.7 1.0
C B:GLY268 4.0 10.6 1.0
CD B:PRO270 4.0 10.3 1.0
CA B:GLY232 4.1 11.9 1.0
C B:PHE306 4.3 18.3 1.0
CD B:PRO257 4.4 9.5 1.0
CA B:GLY268 4.5 10.4 1.0
CG B:PRO270 4.5 11.1 1.0
CG B:PRO257 4.5 9.7 1.0
CB B:SER297 4.6 24.4 1.0
C B:VAL231 4.7 9.9 1.0
C B:LEU304 4.7 20.6 1.0
N B:PHE306 4.8 20.2 1.0
N B:GLY232 4.9 10.7 1.0
C B:SER308 4.9 12.2 1.0
OE1 B:GLU256 4.9 12.8 1.0
CA B:PHE306 4.9 19.6 1.0
CB B:PHE306 4.9 20.2 1.0

Caesium binding site 3 out of 5 in 6c73

Go back to Caesium Binding Sites List in 6c73
Caesium binding site 3 out of 5 in the Tryptophan Synthase Q114A Mutant (Internal Aldimine State) in Complex with N-(4'-Trifluoromethoxybenzenesulfonyl)-2-Amino-1-Ethylphosphate (F9F) with Cesium Ion Bound in the Metal Coordination Site


Mono view


Stereo pair view

A full contact list of Caesium with other atoms in the Cs binding site number 3 of Tryptophan Synthase Q114A Mutant (Internal Aldimine State) in Complex with N-(4'-Trifluoromethoxybenzenesulfonyl)-2-Amino-1-Ethylphosphate (F9F) with Cesium Ion Bound in the Metal Coordination Site within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cs417

b:18.5
occ:0.38
 CS B:CS417 0.0 18.5 0.4
CS B:CS417 1.9 24.6 0.5
O B:GLY232 2.9 20.7 1.0
O B:VAL231 3.3 10.2 1.0
OE1 B:GLU256 3.3 12.8 1.0
O B:GLY268 3.4 10.6 1.0
O B:SER308 3.4 12.8 1.0
CD B:PRO270 3.7 10.3 1.0
C B:GLY232 4.0 13.7 1.0
CG B:PRO270 4.0 11.1 1.0
C B:VAL231 4.1 9.9 1.0
CG1 B:VAL231 4.2 10.9 1.0
CD B:GLU256 4.2 12.4 1.0
CG B:GLU256 4.3 11.1 1.0
CB B:VAL309 4.3 11.3 1.0
CA B:GLY232 4.3 11.9 1.0
C B:SER308 4.5 12.2 1.0
C B:GLY268 4.5 10.6 1.0
O B:PHE306 4.5 21.3 1.0
CG2 B:VAL309 4.5 11.1 1.0
N B:GLY232 4.6 10.7 1.0
CD B:PRO257 4.6 9.5 1.0
CB B:GLU256 4.7 9.4 1.0
N B:PRO270 4.7 10.9 1.0
CA B:VAL309 4.8 11.2 1.0
CB B:VAL231 4.8 9.3 1.0
CA B:ALA269 4.9 9.9 1.0

Caesium binding site 4 out of 5 in 6c73

Go back to Caesium Binding Sites List in 6c73
Caesium binding site 4 out of 5 in the Tryptophan Synthase Q114A Mutant (Internal Aldimine State) in Complex with N-(4'-Trifluoromethoxybenzenesulfonyl)-2-Amino-1-Ethylphosphate (F9F) with Cesium Ion Bound in the Metal Coordination Site


Mono view


Stereo pair view

A full contact list of Caesium with other atoms in the Cs binding site number 4 of Tryptophan Synthase Q114A Mutant (Internal Aldimine State) in Complex with N-(4'-Trifluoromethoxybenzenesulfonyl)-2-Amino-1-Ethylphosphate (F9F) with Cesium Ion Bound in the Metal Coordination Site within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cs418

b:14.7
occ:0.70
 O B:HOH759 2.9 45.1 1.0
O B:THR71 3.0 11.2 1.0
O B:HOH619 3.1 25.1 1.0
O B:THR69 3.2 13.9 1.0
O B:THR66 3.2 12.8 1.0
OG1 B:THR66 3.3 13.5 1.0
O B:HOH694 3.4 29.6 1.0
O B:HOH884 3.8 27.7 1.0
CB B:THR66 3.8 12.7 1.0
C B:THR66 3.9 13.3 1.0
C B:THR71 4.1 10.9 1.0
C B:THR69 4.1 14.1 1.0
OG1 B:THR69 4.3 11.2 1.0
N B:ALA67 4.5 13.7 1.0
N B:THR71 4.5 11.1 1.0
CA B:THR66 4.6 12.4 1.0
N B:THR69 4.6 13.2 1.0
CA B:ALA67 4.6 15.8 1.0
O B:HOH510 4.6 11.4 1.0
N B:GLY68 4.8 17.5 1.0
CA B:THR69 4.9 13.2 1.0
C B:ARG70 4.9 12.1 0.7
N B:THR72 4.9 10.5 1.0
CA B:ARG70 5.0 14.8 0.3
N B:ARG70 5.0 13.4 0.7
N B:ARG70 5.0 14.3 0.3
CA B:THR71 5.0 10.9 1.0
C B:ARG70 5.0 13.0 0.3

Caesium binding site 5 out of 5 in 6c73

Go back to Caesium Binding Sites List in 6c73
Caesium binding site 5 out of 5 in the Tryptophan Synthase Q114A Mutant (Internal Aldimine State) in Complex with N-(4'-Trifluoromethoxybenzenesulfonyl)-2-Amino-1-Ethylphosphate (F9F) with Cesium Ion Bound in the Metal Coordination Site


Mono view


Stereo pair view

A full contact list of Caesium with other atoms in the Cs binding site number 5 of Tryptophan Synthase Q114A Mutant (Internal Aldimine State) in Complex with N-(4'-Trifluoromethoxybenzenesulfonyl)-2-Amino-1-Ethylphosphate (F9F) with Cesium Ion Bound in the Metal Coordination Site within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cs419

b:81.1
occ:0.50
 OE2 B:GLU11 3.9 24.6 0.5
OE1 B:GLU11 4.2 28.3 0.5
O B:HOH561 4.2 20.1 1.0
CD B:GLU11 4.3 23.8 0.5
O B:HOH616 4.4 30.2 1.0
O B:HOH539 4.4 33.8 1.0
CG B:TYR8 4.4 11.6 1.0
CD1 B:TYR8 4.4 12.8 1.0
O B:GLY10 4.5 13.3 1.0
CD2 B:TYR8 4.6 11.7 1.0
O B:HOH614 4.6 39.5 1.0
CE1 B:TYR8 4.6 13.0 1.0
CE2 B:TYR8 4.7 12.0 1.0
CZ B:TYR8 4.7 13.3 1.0
O A:HOH403 4.9 35.7 1.0

Reference:

E.Hilario, M.F.Dunn, L.J.Mueller, L.Fan. Tryptophan Synthase Q114A Mutant (Internal Aldimine State) in Complex with N-(4'-Trifluoromethoxybenzenesulfonyl) -2-Amino-1-Ethylphosphate (F9F) with Cesium Ion Bound in the Metal Coordination Site. To Be Published.
Page generated: Sun Jul 13 22:54:14 2025

Last articles

Mn in 9LJU
Mn in 9LJW
Mn in 9LJS
Mn in 9LJR
Mn in 9LJT
Mn in 9LJV
Mg in 9UA2
Mg in 9R96
Mg in 9VM1
Mg in 9P01
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy