Caesium in PDB 2xq6: Pentameric Ligand Gated Ion Channel Glic in Complex with Cesium Ion (Cs+)

The structure of Pentameric Ligand Gated Ion Channel Glic in Complex with Cesium Ion (Cs+), PDB code: 2xq6 was solved by R.J.C.Hilf, C.Bertozzi, I.Zimmermann, A.Reiter, D.Trauner, R.Dutzler, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.87 / 3.70
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	183.314, 128.310, 164.374, 90.00, 104.04, 90.00
R / Rfree (%)	24.6 / 25.8

The binding sites of Caesium atom in the Pentameric Ligand Gated Ion Channel Glic in Complex with Cesium Ion (Cs+) (pdb code 2xq6). This binding sites where shown within 5.0 Angstroms radius around Caesium atom.
In total only one binding site of Caesium was determined in the Pentameric Ligand Gated Ion Channel Glic in Complex with Cesium Ion (Cs+), PDB code: 2xq6:

Caesium binding site 1 out of 1 in the Pentameric Ligand Gated Ion Channel Glic in Complex with Cesium Ion (Cs+)


Mono view


Stereo pair view

A full contact list of Caesium with other atoms in the Cs binding site number 1 of Pentameric Ligand Gated Ion Channel Glic in Complex with Cesium Ion (Cs+) within 5.0Å range: probe atom residue distance (Å) B Occ C:Cs1317 b:0.8 occ:1.00 OG1 C:THR225 3.5 0.3 1.0 OG1 E:THR225 3.5 0.3 1.0 OE2 A:GLU221 3.8 0.7 1.0 OE2 C:GLU221 3.8 1.0 1.0 CG2 E:THR225 4.0 0.5 1.0 OE2 E:GLU221 4.0 0.5 1.0 OG1 B:THR225 4.1 0.4 1.0 OG1 A:THR225 4.1 0.3 1.0 OE2 B:GLU221 4.2 0.5 1.0 CG2 C:THR225 4.3 0.8 1.0 CB E:THR225 4.4 0.2 1.0 CG2 B:THR225 4.4 0.4 1.0 CB C:THR225 4.4 0.1 1.0 OG1 D:THR225 4.5 0.8 1.0 OE2 D:GLU221 4.5 0.0 1.0 OE1 C:GLU221 4.6 0.0 1.0 CD C:GLU221 4.6 0.7 1.0 CD A:GLU221 4.7 0.7 1.0 OE1 A:GLU221 4.8 0.2 1.0 CG2 D:THR225 4.8 0.5 1.0 CB B:THR225 4.9 0.5 1.0 CG2 A:THR225 5.0 0.9 1.0

R.J.C.Hilf, C.Bertozzi, I.Zimmermann, A.Reiter, D.Trauner, R.Dutzler. Structural Basis of Open Channel Block in A Prokaryotic Pentameric Ligand-Gated Ion Channel Nat.Struct.Mol.Biol. V. 17 1330 2010.
ISSN: ISSN 1545-9993
PubMed: 21037567
DOI: 10.1038/NSMB.1933